As far as domesticated animals go, the rabbit is, frankly, a noob. French monks tamed wild rabbits about 1,400 years ago, compared with 10,000 years for sheep and up to 30,000 years for dogs. What separates a timid wild bunny and a calm tame rabbit are about 100 little tweaks in genetic information, biologists recently found, but no major differences in a single gene.
It's quite unlikely there's such a thing as a "domestication gene," says researcher Leif Andersson, a genetic expert who studies domesticated animals at Texas A&M; University, in a statement.
The key changes between wild and tame rabbits is how afraid these animals become around humans. "Selection during domestication might have focused on tameness and lack of fear," University of Leicester biologist Pat Heslop-Harrison tells the New Scientist. "As a farmer, you neither want the animal to hurt you, nor for the animal to die from stress."
Bunnies, thanks to this genetic tuning, are much less likely to flee from a lap or safe embrace than their wild counterparts. Just look at this Flemish Giant: