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The ASPCA joined with local law enforcement to conduct the seizure in Needham, Alabama, after several new owners complained that dogs obtained from the facility were severely sick.
Investigators found 130 dogs in "filthy" and "deplorable" conditions, along with puppy remains, according to the ASPCA. Many of the dogs were malnourished or dehydrated, and suffered from dental disease, hypothermia and ocular damage.
They're currently receiving medical and behavioral treatment at an undisclosed location while the investigation unfolds.
"It's clear that profit was put above the well-being of these dogs," Tim Rickey, vice president for ASPCA Field Investigations and Response, said in a statement. "As is the case with most puppy mills, these dogs were treated as products for sale and not valued as living beings."
Meanwhile, the facility's owners, Rebecca Miller and Janice Freeman, have been arrested and are awaiting charges. Law enforcement officers also found illegal drugs and $20,000 in cash on the premises, the ASPCA reported.